The Wall Street Journal

Before signing up with the site, a woman with Parkinson’s disease tried to raise money for research the old-fashioned way — by talking to friends, says Alexander Blass, the founder of Reality Charity. The result: $100 in donations for a 2006 walk in New York City. The following year, she posted an appeal on Reality Charity — and raised $1,650 from 25 people. Much of the money came from people she knew but hadn’t seen in 20 years, according to a posting on the site’s Donor Wall.